Document 0302 DOCN M9460302 TI Recent advances in the chemotherapy of AIDS. DT 9404 AU Verma S; University of Illinois at Chicago. SO Indian J Physiol Pharmacol. 1994 Jan;38(1):5-16. Unique Identifier : AIDSLINE MED/94178840 AB Acquired immunodeficiency syndrome (AIDS) continues to grow unabated and in pandemic proportions around the world. The complexity and high mutational ability of the etiologic agent, human immunodeficiency virus, has posed an unprecedented threat toward the chemotherapy of AIDS. Use of contemporary virology to unfold the mystery of HIV-1 and the discovery of key molecular targets for chemotherapeutic intervention has accelerated the quest for safe and effective anti-HIV agents. The vital stages in viral replication amenable to inhibition by novel chemical entities and representative examples from diverse chemical classes as potential anti-AIDS agents are presented in this review. DE Acquired Immunodeficiency Syndrome/*DRUG THERAPY/IMMUNOLOGY Antiviral Agents/*THERAPEUTIC USE Human *HIV-1/DRUG EFFECTS/IMMUNOLOGY/PHYSIOLOGY JOURNAL ARTICLE REVIEW REVIEW, TUTORIAL SOURCE: National Library of Medicine. NOTICE: This material may be protected by Copyright Law (Title 17, U.S.Code).