Document 0307
 DOCN  M9460307
 TI    Reversible myoclonic encephalopathy revealing the AIDS-dementia complex.
 DT    9404
 AU    Thomas P; Borg M; Service de Neurologie, Hopital Pasteur, Nice, France.
 SO    Electroencephalogr Clin Neurophysiol. 1994 Feb;90(2):166-9. Unique
       Identifier : AIDSLINE MED/94178235
 AB    A 40-year-old HIV-positive right handed homosexual man was admitted for
       progressive mental deterioration coexisting with permanent segmental
       middle-amplitude arrhythmic, asynchronous and asymmetrical myoclonic
       jerks. EEG showed fronto-central bursts of rhythmic triphasic 1.5-2 Hz
       sharp waves similar to the characteristic periodic pattern of
       Jakob-Creutzfeldt disease. Biological procedures were negative, thus
       eliminating a metabolic encephalopathy. Dramatic neurological
       improvement occurred shortly after initiation of i.v. and then oral
       zidovudine which produced perfect EEG normalisation. This unusual
       electroclinical presentation of the AIDS-dementia complex underlines the
       fact that this affection may present a diagnostic challenge,
       particularly in individuals in whom HIV infection is unknown.
 DE    Adult  AIDS Dementia Complex/*COMPLICATIONS
       Brain/PATHOLOGY/*PHYSIOPATHOLOGY  Case Report  Electroencephalography
       Epilepsy, Myoclonic/ETIOLOGY/*PHYSIOPATHOLOGY  Human  Magnetic Resonance
       Imaging  Male  JOURNAL ARTICLE

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