Document 0309
 DOCN  M9460309
 TI    Successful treatment of Kaposi's sarcoma with interferon-alpha in a
       patient with acquired immunodeficiency syndrome.
 DT    9404
 AU    Yeh TS; Wang CR; Wong WW; Jeng GW; Chen MY; Liu CY; Chuang CY; Chen WY;
       Department of Internal Medicine, National Taiwau University; Hospital.
 SO    Chung Hua Min Kuo Wei Sheng Wu Chi Mien I Hsueh Tsa Chih. 1993
       Feb;26(1):38-43. Unique Identifier : AIDSLINE MED/94178132
 AB    Although combined therapy with interferon-alpha and zidovudine may be
       safely administered to some patients with the acquired immunodeficiency
       syndrome (AIDS) and Kaposi sarcoma, no ethnic Chinese patient has been
       successfully treated before in this area. This case report concerns a
       47-year-old male with a history of bisexuality who had suffered from
       oral ulcers for half a year, Human immunodeficiency virus (HIV) serology
       was positive, and pathology of the oral ulcers disclosed Kaposi sarcoma.
       Combination therapy with zidovudine and interferon-alpha was initiated.
       The patient received a low-dose regimen of 5.0 million U
       interferon-alpha s.c. per day for 8 weeks and 5 million U twice a week
       for another 8 weeks. The oral ulcers faded away without recurrence. This
       report also reviews the literatures on treatment of AIDS-related Kaposi
       sarcoma with interferon.
 DE    Acquired Immunodeficiency Syndrome/*COMPLICATIONS/DRUG THERAPY  Case
       Report  Human  Interferon-alpha/*THERAPEUTIC USE  Male  Middle Age
       Sarcoma, Kaposi's/*THERAPY  T4 Lymphocytes/IMMUNOLOGY
       Zidovudine/THERAPEUTIC USE  JOURNAL ARTICLE

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