Document 0427 DOCN M9460427 TI Menstrual symptoms in women infected by the human immunodeficiency virus. DT 9404 AU Shah PN; Smith JR; Wells C; Barton SE; Kitchen VS; Steer PJ; Department of Obstetrics and Gynaecology, Charing Cross and; Westminster Medical School, London, United Kingdom. SO Obstet Gynecol. 1994 Mar;83(3):397-400. Unique Identifier : AIDSLINE MED/94173528 AB OBJECTIVE: To determine whether there is a higher prevalence of menstrual symptoms in women seropositive for the human immunodeficiency virus (HIV) compared to a matched control group and to examine the relation between menstrual symptomatology and immunosuppression. METHODS: In a cross-sectional study, 55 HIV-seropositive women and a matched control group underwent detailed gynecologic assessment. The prevalence of regular cycles, oligomenorrhea, amenorrhea, menorrhagia, dysmenorrhea, and dyspareunia was assessed in the two groups. Any association with clinical disease or CD4 lymphocyte count was sought. RESULTS: There were no significant differences in the prevalence of oligomenorrhea, amenorrhea, menorrhagia, dysmenorrhea, or dyspareunia between the groups. Furthermore, no differences were demonstrated between symptomatic and asymptomatic women infected by HIV, nor was any correlation found between CD4 lymphocyte count and menstrual loss or dysmenorrhea. CONCLUSION: Infection with HIV and related immunosuppression do not seem to have a clinically significant effect on menstruation. DE Adult Cross-Sectional Studies Female Human HIV Seropositivity/*COMPLICATIONS Menstruation Disorders/EPIDEMIOLOGY/*ETIOLOGY Middle Age Prevalence Support, Non-U.S. Gov't JOURNAL ARTICLE SOURCE: National Library of Medicine. NOTICE: This material may be protected by Copyright Law (Title 17, U.S.Code).