Document 0437
 DOCN  M9460437
 TI    Perinatal transmission of HIV-2 infection in malnourished children in
       Guinea Bissau.
 DT    9404
 AU    Ferro A; Gomez P; Andrian C; Perra A; Frongia O; Sechi MA; Sabbatani S;
       Lillo F; Varnier OE; Blood Bank, Hospital Nacional Simao Mendes, Bissau,
       Republica da; Guine.
 SO    Microbiologica. 1994 Jan;17(1):61-4. Unique Identifier : AIDSLINE
       MED/94173182
 AB    Since there have been a few reports of pediatric HIV-2 infection. We
       therefore investigated the perinatal transmission of HIV-2 in 147
       malnourished and 164 well-nourished children attending a health center
       in the northern part of Guinea Bissau. Specific HIV-2 antibodies were
       detected in 17 mothers and in 2 malnourished children, one of them with
       pediatric AIDS. This study demonstrates that mother to child
       transmission of HIV-2 infection occurs in Guinea Bissau and suggests
       that there is an increased likelihood of detecting HIV-2 infection in
       malnourished children. The high seroprevalence of HIV-2 in a rural
       population without known risk factors may represent a hidden threat to
       mother/child health.
 DE    Acquired Immunodeficiency Syndrome/COMPLICATIONS/*EPIDEMIOLOGY/
       *TRANSMISSION  Blotting, Western  Case Report  Child Nutrition
       Disorders/*COMPLICATIONS  Child, Preschool  Enzyme-Linked Immunosorbent
       Assay  Female  Guinea-Bissau/EPIDEMIOLOGY  Human  HIV Antibodies/BLOOD
       HIV Infections/COMPLICATIONS/*EPIDEMIOLOGY/*TRANSMISSION  HIV
       Seropositivity  HIV-1/IMMUNOLOGY  *HIV-2/IMMUNOLOGY  Infant  Male
       Support, Non-U.S. Gov't  JOURNAL ARTICLE

       SOURCE: National Library of Medicine.  NOTICE: This material may be
       protected by Copyright Law (Title 17, U.S.Code).