Document 0485
 DOCN  M9460485
 TI    Unsuspected Pneumocystis carinii pneumonia and vertically acquired HIV
       infection in infants requiring intensive care [see comments]
 DT    9404
 AU    Tasker RC; Wilkinson K; Slater TJ; Novelli V; Paediatric Intensive Care
       Unit, Hospital for Sick Children,; London.
 SO    BMJ. 1994 Feb 12;308(6926):462-3. Unique Identifier : AIDSLINE
       MED/94169784
 CM    Comment in: BMJ 1994 Feb 12;308(6926):425-6
 AB    When an infant develops acute respiratory failure of sufficient severity
       to necessitate supportive mechanical ventilation a cause should always
       be sought. A chest radiograph showing predominantly interstitial lung
       disease and an infant's failure to respond to standard antibiotic
       treatment are indications for non-bronchoscopic bronchoalveolar lavage.
       If P carinii pneumonia is diagnosed a congenital immunodeficiency should
       be sought and the parents counselled about HIV infection. Earlier
       investigation may be indicated by features of immunodeficiency when
       taking a history, performing a general examination, or analysing the
       results of basic haematological testing.
 DE    Case Report  Female  Human  HIV Infections/*COMPLICATIONS/TRANSMISSION
       Infant  Intensive Care, Neonatal  Male  Pneumonia, Pneumocystis
       carinii/*COMPLICATIONS/THERAPY  JOURNAL ARTICLE

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