Document 0507
 DOCN  M9460507
 TI    Buschke-Loewenstein tumour infiltrating pelvic organs.
 DT    9404
 AU    Grassegger A; Hopfl R; Hussl H; Wicke K; Fritsch P; Department of
       Dermatology, University of Innsbruck, Austria.
 SO    Br J Dermatol. 1994 Feb;130(2):221-5. Unique Identifier : AIDSLINE
       MED/94169061
 AB    We report a 42-year-old HIV-negative patient with a 12-year history of
       exceptionally extensive genital warts and coexisting verrucous carcinoma
       of the anogenital region (Buschke-Loewenstein tumour). Masses of both
       tumour and viral papillomas infiltrated the external genitalia, perineum
       and buttocks, pelvic diaphragm and parts of the lesser pelvis, as well
       as the urethra, prostate and parts of the urinary bladder, necessitating
       repeated surgical intervention and plastic reconstruction. Adjuvant
       interferon-alpha therapy was given without any lasting effects. Human
       papillomavirus type 6 was detected by DNA in situ hybridization and
       Southern blot analysis.
 DE    Adult  Anus Neoplasms/MICROBIOLOGY/*PATHOLOGY  Bladder
       Neoplasms/MICROBIOLOGY/PATHOLOGY  Carcinoma,
       Verrucous/MICROBIOLOGY/*PATHOLOGY  Case Report  Condylomata
       Acuminata/*PATHOLOGY  Genital Neoplasms, Male/MICROBIOLOGY/*PATHOLOGY
       Human  Male  Neoplasm Invasiveness  Papillomavirus, Human/ISOLATION &
       PURIF  Rectal Neoplasms/MICROBIOLOGY/PATHOLOGY  JOURNAL ARTICLE

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