Document 0524
 DOCN  M9460524
 TI    HIV-1 and parasitic infections in rural Tanzania.
 DT    9404
 AU    Atzori C; Bruno A; Chichino G; Cevini C; Bernuzzi AM; Gatti S; Comolli
       G; Scaglia M; Laboratory of Clinical Parasitology, University-IRCCS
       Policlinico; S. Matteo, Pavia, Italy.
 SO    Ann Trop Med Parasitol. 1993 Dec;87(6):585-93. Unique Identifier :
       AIDSLINE MED/94168472
 AB    A sample of 300 sexually-active adults was selected at random from
       patients, from the rural area of Malenga Makali, Tanzania, who were
       attending a dispensary because they had diarrhoea of at least 2 weeks'
       duration. The potential associations between the patient's health (in
       terms of the World Health Organization's clinical definition of AIDS),
       HIV-1 seroprevalence and malaria and other parasitic infections were
       then investigated. Although, HIV-1 seroprevalence was 20.6% overall, the
       level of seroprevalence was directly correlated with the distance
       between the patients' home villages and the nearest main road. Strict
       application of the clinical definition of AIDS gave 98.7% specificity,
       46% sensitivity and a predictive value of 90.6% when validated by HIV-1
       seropositivity. Although malaria infection was more common in HIV-1
       seropositives than in the seronegatives, the intensity of the Plasmodium
       falciparum infections, intestinal amoebiasis and giardiasis did not
       appear to be correlated with HIV-1 infection. In contrast, intestinal
       infections with Cryptosporidium parvum and Isospora belli were virtually
       restricted to HIV-1 seropositive individuals who had had diarrhoea for a
       relatively long time.
 DE    Acquired Immunodeficiency Syndrome/COMPLICATIONS/*EPIDEMIOLOGY/
       PARASITOLOGY  Adolescence  Adult  Age Factors  Female  Human  *HIV
       Seroprevalence  Intestinal Diseases,
       Parasitic/COMPLICATIONS/*EPIDEMIOLOGY  Malaria,
       Falciparum/COMPLICATIONS/*EPIDEMIOLOGY  Male  Rural Population  Sex
       Factors  Support, Non-U.S. Gov't  Tanzania/EPIDEMIOLOGY  JOURNAL ARTICLE

       SOURCE: National Library of Medicine.  NOTICE: This material may be
       protected by Copyright Law (Title 17, U.S.Code).