Document 0569
 DOCN  M9460569
 TI    [Epidemiology of AIDS in Barcelona (1981-1991) (II). A study of
       mortality and survival]
 DT    9404
 AU    Cayla JA; Artazcoz L; Iglesias B; Jansa JM; Plasencia A; Servicio de
       Epidemiologia, Institut Municipal de la Salut,; Barcelona.
 SO    Med Clin (Barc). 1994 Feb 5;102(4):129-35. Unique Identifier : AIDSLINE
       MED/94166538
 AB    BACKGROUND: To analyze the evolution of the mortality and survival of
       AIDS patients in Barcelona. METHODS: In the mortality study patients
       living in the city and who were detected from 1981-1991 by an active
       surveillance system were included. The survival analysis was restricted
       to patients from 1988-1990 (same definition of AIDS and longer patient
       follow up). The Kaplan-Meier and Cox methods were used. RESULTS: In 1991
       the rate of mortality was 14.1/100,000, similar to 1990 (14.0/100,000)
       and greater or much higher than the preceding years. Lethality increased
       in agreement with the semester of case diagnosis, with values between
       100% (first years of the epidemic) and 23% (last semester) being
       registered. The accumulated probability of survival at 365 days was of
       65.2% (CI 95%, 62.2-68.0) and 32.2% (CI 28.8-35.7) at 1.095 days. Median
       survival of the whole population was 669 days. Statistically significant
       differences were observed according to the year of diagnosis, prison
       history, antiretroviral treatment, disease diagnosis, transmission
       group, district of residence and age group but not according to sex.
       Multivariate analysis only discarded the influence of prison history.
       CONCLUSIONS: Mortality by AIDS has enormously increased. Survival
       analysis demonstrated better prognosis in the youngest cases, those
       residing in more favorable socioeconomic districts, diagnoses from
       diseases added to the old definition of AIDS, the IVDA and homosexual
       risk groups and the most recently diagnosed cases.
 DE    Acquired Immunodeficiency Syndrome/EPIDEMIOLOGY/*MORTALITY  Adult
       English Abstract  Female  Human  Male  Middle Age  Spain/EPIDEMIOLOGY
       Support, Non-U.S. Gov't  Survival Analysis  JOURNAL ARTICLE

       SOURCE: National Library of Medicine.  NOTICE: This material may be
       protected by Copyright Law (Title 17, U.S.Code).