Document 0602
 DOCN  M9460602
 TI    Pupil cycle time and human immunodeficiency virus (HIV) infection.
 DT    9404
 AU    Maclean H; Dhillon B; Princess Alexandra Eye Pavilion, Edinburgh, UK.
 SO    Eye. 1993;7 ( Pt 6):785-6. Unique Identifier : AIDSLINE MED/94164334
 AB    The pupil cycle time (PCT) was measured in 22 HIV-positive patients and
       22 age/sex-matched controls. Of the HIV-positive group, 13 (59%) met the
       Centre for Disease Control classification of acquired immunodeficiency
       syndrome (AIDS) defining illness. There was a highly statistically
       significant difference in the PCT between the HIV-infected group and the
       control group (p < 0.0001, Student's t-test). Within the HIV-infected
       group there was no statistically significant difference in the PCT
       between those patients with full-blown AIDS and the others. This study
       suggests that HIV infection may be associated with subclinical ocular
       autonomic dysfunction even in the earlier stages of HIV infection.
 DE    Acquired Immunodeficiency Syndrome/PHYSIOPATHOLOGY  Adult  Autonomic
       Nervous System Diseases/PHYSIOPATHOLOGY  Female  Human  HIV
       Infections/*PHYSIOPATHOLOGY  Male  Reflex, Pupillary/*PHYSIOLOGY  Time
       Factors  JOURNAL ARTICLE

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