Document 0633
 DOCN  M9460633
 TI    [Fiber optics bronchoscopy yield and predictive clinical, analytical,
       and radiologic factors in the etiologic diagnosis of pulmonary pathology
       in patients with HIV infection]
 DT    9404
 AU    Supervia Caparros A; Minguez Maso S; Galofre Alvaro N; Knobel Freud H;
       Currull Serrano V; Sanjuas Benito C; Servicio de Medicina Interna,
       Hospital de l'Esperanca,; Barcelona.
 SO    An Med Interna. 1993 Nov;10(11):532-6. Unique Identifier : AIDSLINE
       MED/94162445
 AB    The aim of this study was to assess the diagnostic performance of
       fibrobronchoscopy (FBS) in the pulmonary pathology of HIV-positive
       patients, in order to study the effect of several factors on such
       performance and to evaluate if these factors could guide the etiologic
       diagnosis. A retrospective study of 49 FBS with bronchoalveolar lavage
       (BAL) was performed in 44 HIV-positive patients. The diagnostic
       performance of FBS with BAL was 71.4%, with no significant modifications
       caused by previous prophylactic or empirical therapies, time of clinical
       evolution, radiological pattern, presence of hypoxemia or CD4 count. On
       the contrary, a high LDH was associated to a higher diagnostic
       performance. Diagnosis: Pneumonia by Pneumocystis carinii (36.7%), M.
       tuberculosis (28.6%) and bacterial pneumonias (16.3%). The presence of
       biliary adenopathies, evolution longer than 1 week and pO2 > 80 mm Hg
       had a high sensitivity of 28.5% and a specificity of 97% for the
       diagnosis of tuberculosis, with a positive predictive value of 80% and a
       negative predictive value of 77.7%.
 DE    Adult  Bronchoalveolar Lavage Fluid  *Bronchoscopy  Comparative Study
       English Abstract  Female  Fiber Optics  Human  HIV
       Infections/*COMPLICATIONS  Lung Diseases/*DIAGNOSIS/ETIOLOGY  Male
       Pneumonia/DIAGNOSIS/ETIOLOGY  Predictive Value of Tests  Retrospective
       Studies  Sensitivity and Specificity  Tuberculosis,
       Pulmonary/DIAGNOSIS/ETIOLOGY  JOURNAL ARTICLE

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