Document 0671 DOCN M9460671 TI HIV-encephalopathy: should we await a catastrophe before screening? DT 9404 AU Patt HO; Pagano MA; Garau MA; Research Department Fernandez Hospital, Buenos Aires, Argentina. SO Aviat Space Environ Med. 1994 Jan;65(1):70-3. Unique Identifier : AIDSLINE MED/94161681 AB Human Immunodeficiency Virus (HIV)-encephalopathy (formerly AIDS Dementia Complex, or ADC) is characterized by global impairment of intellectual and cognitive functions, personality and behavioral disturbances, decreased memory, inability to concentrate, and apathy. Its motor dysfunction is manifested by impaired speech, gait, and coordination, and by psychomotor retardation. Several scientific reports indicate that ADC may be the earliest, and, at times, the only evidence of human immunodeficiency virus infection, and may present a diagnostic challenge, particularly in the aviation context. Several aviation medicine specialists have pointed out the safety questions raised by this condition when it presents in otherwise asymptomatic individuals. Since October 1985, U.S. military pilots have been tested for the presence of HIV antibody and grounded if found positive. In May 1991, the Executive Council of the Aerospace Medical Association approved a position statement that supports testing of pilots for infection by HIV, and maintains that individuals confirmed to be infected should be found medically disqualified for flying duties. While bureaucrats delay in resolving HIV mandatory screening, HIV-encephalopathy may be precipitously brought to light, with symptoms involving ocular motor disorders such as dissociated nystagmus, gaze-evoked nystagmus, and impaired saccadic function and smooth pursuit, frequent signs of HIV cerebellar and pontomesencephalic dysfunction. DE Aerospace Medicine *Aviation AIDS Dementia Complex/*DIAGNOSIS AIDS Serodiagnosis Human *Military Personnel Occupations United States JOURNAL ARTICLE SOURCE: National Library of Medicine. NOTICE: This material may be protected by Copyright Law (Title 17, U.S.Code).