Document 0683
 DOCN  M9460683
 TI    Pathomorphological and immunohistological changes in lymph nodes of cows
       spontaneously infected by bovine leukaemia virus.
 DT    9404
 AU    Levkut M; Plank L; Levkutova M; Konrad V; Department of Pathological
       Anatomy, University of Veterinary; Medicine, Kosice, Slovakia.
 SO    Acta Vet Hung. 1993;41(1-2):89-101. Unique Identifier : AIDSLINE
       MED/94160873
 AB    Prescapular lymph nodes from 109 cows seropositive to bovine leukaemia
       virus (BLV) were subjected to histologic, cytochemical and in dubious
       cases also to immunohistologic examination for the presence of light
       chains of bovine immunoglobulin (Ig) kappa or lambda. By their
       morphological features, the histologically detected changes were divided
       into B-zonal hyperplasia (23 cases, 21.1%), T-zonal hyperplasia (52
       cases, 47.7%), pulp proliferation (6 cases, 5.5%), hyperplasia of mixed
       type (18 cases, 16.5%), and atrophy (10 cases, 9.2%). Some changes
       resembled those reported in infections with human or feline
       immunodeficiency virus. Eosinophilic infiltration was a frequent
       feature. Immunohistochemical examination revealed only a lambda Ig chain
       in the cytoplasm of plasma cells or plasmacytoid cells and immunoblasts
       in pulp proliferation. Cytochemical examination showed a considerable
       number of cells with a diffuse positive reaction to acid phosphatase
       (AP).
 DE    Animal  Cattle  Enzootic Bovine Leukosis/IMMUNOLOGY/*PATHOLOGY  Female
       Immunoglobulins, kappa-Chain/ANALYSIS  Immunoglobulins,
       lambda-Chain/ANALYSIS  Immunohistochemistry  *Leukemia Virus, Bovine
       Lymph Nodes/IMMUNOLOGY/*PATHOLOGY  JOURNAL ARTICLE

       SOURCE: National Library of Medicine.  NOTICE: This material may be
       protected by Copyright Law (Title 17, U.S.Code).