Document 0736
 DOCN  M9460736
 TI    Pathways to the impairment of human nutritional status by
       gastrointestinal pathogens.
 DT    9404
 AU    Solomons NW; Center for Studies of Sensory Impairment, Aging and
       Metabolism; (CeSSIAM), Hospital de Ojos y Oidos, Guatemala City,
       Guatemala.
 SO    Parasitology. 1993;107 Suppl:S19-35. Unique Identifier : AIDSLINE
       MED/94159382
 AB    Gastrointestinal pathogens are of three varieties, those that can, and
       often do, take the life of the host, those that infect transiently and
       rarely are life-threatening, and those (parasites) that establish a
       relatively prolonged residence or colonization of the host's alimentary
       tract. In the case of the second form, if infections are recurrent, both
       catabolic effects during the episode and failure to digest foods and/or
       absorb nutrients results. Similarly, catabolic wastage through
       activation of the acute phase response, and interference with the host's
       acquisition of nutrients by maldigestion, malabsorption, intestinal
       losses and competition with the parasite burden can impair growth and
       nutrition with helminthic infections. Growth and nutrition with respect
       to all of the macronutrients and virtually all of the micronutrients
       have been documented to be adversely affected by gastrointestinal
       pathogens. For its burgeoning importance as a worldwide health problem,
       both with the HIV virus as a direct intestinal pathogen and with the
       opportunistic gut infections occurring in the immunocompromised host,
       AIDS represents the emerging context of the impairment of nutritional
       status by intestinal pathogens.
 DE    Animal  AIDS-Related Opportunistic Infections  Bacterial
       Infections/COMPLICATIONS/PHYSIOPATHOLOGY  Child  Child, Preschool
       Diarrhea/COMPLICATIONS/PARASITOLOGY
       Gastroenteritis/COMPLICATIONS/*PHYSIOPATHOLOGY
       Helminthiasis/COMPLICATIONS/PHYSIOPATHOLOGY  Human  Infant  Intestinal
       Diseases, Parasitic/COMPLICATIONS/*PHYSIOPATHOLOGY
       Intestines/MICROBIOLOGY/PHYSIOPATHOLOGY/PARASITOLOGY  Nutrition
       Disorders/COMPLICATIONS/*PHYSIOPATHOLOGY  *Nutritional Status  Protozoan
       Infections/COMPLICATIONS/PHYSIOPATHOLOGY  Virus
       Diseases/COMPLICATIONS/PHYSIOPATHOLOGY  JOURNAL ARTICLE  REVIEW  REVIEW,
       ACADEMIC

       SOURCE: National Library of Medicine.  NOTICE: This material may be
       protected by Copyright Law (Title 17, U.S.Code).