Document 0866
 DOCN  M9460866
 TI    [Immune function of rheumatoid arthritis treated by medicated-bath
       therapy in Tibetan medicine]
 DT    9404
 AU    Zhao SL; Geng PL; Sang J; Dept. of Microbiology and Immunology, Quinghai
       Medical College,; Xining.
 SO    Chung Kuo Chung Hsi I Chieh Ho Tsa Chih. 1993 Aug;13(8):467-70, 452-3.
       Unique Identifier : AIDSLINE MED/94154461
 AB    The changes of the immune function of rheumatoid arthritis before and
       after the Tibetan medicated-bath was observed. It showed a higher level
       of the rheumatoid factor (RF) titre, immunoglobulin (Ig) G, M, A and CD4
       cells, but the CD8 cells was obviously lower before the treatment.
       Clinical data indicated that the medicated-bath had significant
       effective rate. In order to elucidate the mechanism of the
       medicated-bath upon rheumatoid arthritis the RF titre, Ig level,
       complement C3, 3H-TdR incorporated with lymphocytes transformation and
       CD3, CD4, CD8 cell level were assayed. Results showed that RF titre
       decreased after the bath and the negative transforming rate reached
       70.6%, Ig level obviously dropped as well as the number of CD4 cells
       while CD8 cell level increased. The transforming stimulation index of
       lymphocyte cells obviously decreased. All of the above mentioned showed
       that there was a higher concentration of the enhancing factor of
       interleukin-2 (IL2-EF) involved in lymphocyte culture of rheumatoid
       arthritis patients. They suggested that the Tibetan medicated-bath had
       an immunomodulating effect on rheumatoid arthritis patients through
       increasing the level of CD8 cells and reducing CD4 cells.
 DE    Adjuvants, Immunologic/PHARMACOLOGY/THERAPEUTIC USE  Adolescence  Adult
       Arthritis, Rheumatoid/IMMUNOLOGY/*THERAPY  Balneology  *Baths  CD4-CD8
       Ratio  Drugs, Chinese Herbal/*ADMINISTRATION & DOSAGE/PHARMACOLOGY
       English Abstract  Female  Human  Interleukin-2/BLOOD  Male  Middle Age
       Rheumatoid Factor/*BLOOD  JOURNAL ARTICLE

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