Document 0901
 DOCN  M9460901
 TI    Serum antibodies to viral pathogens and Toxoplasma gondii in
       HIV-infected individuals.
 DT    9404
 AU    Flo RW; Nilsen A; Voltersvik P; Haukenes G; Medical Department B,
       Haukeland Hospital, University of Bergen,; Norway.
 SO    APMIS. 1993 Dec;101(12):946-52. Unique Identifier : AIDSLINE
       MED/94153541
 AB    Sera from 38 HIV-infected individuals were examined longitudinally for
       antibodies to viruses that may increase morbidity in HIV infection, as
       well as commensal viruses and Toxoplasma gondii. HTLV infection was seen
       in Norway for the first time as four patients had antibodies to HTLV-II
       and one had antibodies to HTLV-I. Antibodies to hepatitis B virus (HBV)
       were found in 47.2%, while 21.6% of the patients had antibodies to
       hepatitis C virus (HCV). There was no evidence of acquisition of HBV or
       HVC during the mean observation period of 2 years. A titre increase in
       CMV antibody with time was observed for 7 out of 21 patients and a
       decrease for 2 patients. For Epstein-Barr virus, herpes simplex,
       varicella-zoster, rubella and measles viruses, human polyomavirus BK as
       well as for Toxoplasma gondii, antibody prevalences and titres were
       within the range seen in normal populations. Also, no longitudinal
       changes were observed in titres of these antibodies, indicating that
       humoral immunity remained intact during the study period. The high
       prevalences of HTLV-I/II, HBV and HCV antibodies in HIV-infected
       patients reflect common modes of virus transmission, and the
       fluctuations in CMV antibody titre are indicative of reactivations. Such
       coinfections may influence disease progression.
 DE    Adult  Animal  Antibodies, Protozoan/*BLOOD  Antibodies, Viral/*BLOOD
       Cytomegalovirus/IMMUNOLOGY  Enzyme-Linked Immunosorbent Assay  Female
       Hepatitis Antibodies/BLOOD  Hepatitis B Antibodies/BLOOD  Hepatitis C
       Viruses/IMMUNOLOGY  Herpesvirus 4, Human/IMMUNOLOGY  Human  HIV
       Infections/BLOOD/*IMMUNOLOGY  HTLV-I Antibodies/BLOOD  HTLV-II
       Antibodies/BLOOD  Longitudinal Studies  Male  Middle Age  Support,
       Non-U.S. Gov't  Time Factors  Toxoplasma/*IMMUNOLOGY  JOURNAL ARTICLE

       SOURCE: National Library of Medicine.  NOTICE: This material may be
       protected by Copyright Law (Title 17, U.S.Code).