Document 0902
 DOCN  M9460902
 TI    [Disseminated histoplasmosis in children]
 DT    9404
 AU    Ramon-Garcia G; Pena-Alonso YR; Ontiveros-Nevares PG; Departamento de
       Patologia, Hospital Infantil de Mexico Federico; Gomez, Mexico, D.F.
 SO    Bol Med Hosp Infant Mex. 1993 Dec;50(12):870-5. Unique Identifier :
       AIDSLINE MED/94153453
 AB    Disseminated histoplasmosis is a rare and severe form of the infection
       due to the fungus Histoplasma capsulatum. This form of disease is seen
       mainly in patients with some sort of immune deficiency either primary or
       secondary, in children under two years and in elderly people. An autopsy
       review at the Hospital Infantil de Mexico Federico Gomez disclosed eight
       cases of lethal disseminated histoplasmosis in an eight year period. All
       patients were malnourished, one of them also had a primary
       immunodeficiency an another had acquired immune deficiency syndrome. The
       age range was from two months to seven years; five patients were males.
       The organs more frequently affected were lungs, liver and spleen. In
       seven patients the diagnosis was established at postmortem study. The
       patients came from Morelos, Veracruz, Guerrero and Chiapas, regions
       considered endemic for histoplasmosis. A careful analysis of the
       clinical symptoms together with a detailed information of the living
       environment of patients, will lead to an accurate diagnosis and
       management of children with this disease.
 DE    Autopsy  AIDS-Related Opportunistic Infections/PATHOLOGY  Child  Child,
       Preschool  English Abstract  Female  Histoplasmosis/DIAGNOSIS/*PATHOLOGY
       Human  Immunologic Deficiency Syndromes/PATHOLOGY  Infant  Male  Mexico
       Nutrition Disorders/PATHOLOGY  JOURNAL ARTICLE

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