Document 0024
 DOCN  M9460024
 TI    [Syndrome of macrophagic activation with hemophagocytosis in human
       immunodeficiency virus infection]
 DT    9408
 AU    Pellegrin JL; Merlio JP; Lacoste D; Barbeau P; Brossard G; Beylot J;
       Leng B; Clinique de Medecine Interne et Maladies Infectieuses, Hopital;
       Saint-Andre, Bordeaux.
 SO    Rev Med Interne. 1992 Nov;13(6):438-40. Unique Identifier : AIDSLINE
       MED/94225092
 AB    The authors report two cases of hematophagic histiocytosis in HIV
       positive patients. In the first case, a patient with Kaposi sarcoma and
       Mycobacterium avium infection had a rapidly deteriorating course with
       progressive pancytopenia and death, as generally described in the
       literature. In the second case, hematophagic histiocytosis appeared
       during HIV primo infection and reversed spontaneously. Although few
       cases of hemophagocytic syndrome have been reported in HIV positive
       patient, it could represent an underestimated cause of pancytopenia.
       Both opportunistic microorganisms and HIV are able to cause hematophagic
       histiocytosis.
 DE    Adult  Case Report  English Abstract  Fatal Outcome  Histiocytosis,
       Non-Langerhans-Cell/BLOOD/*MICROBIOLOGY  Human  HIV
       Infections/CLASSIFICATION/*COMPLICATIONS  *HIV-1  *Macrophage Activation
       Male  Pancytopenia/BLOOD/ETIOLOGY  Remission, Spontaneous  JOURNAL
       ARTICLE  REVIEW  REVIEW OF REPORTED CASES

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