Document 0078
 DOCN  M9460078
 TI    Prevalence and epidemiologic correlates of human T cell lymphotropic
       virus infection among intravenous drug users.
 DT    9408
 AU    Schwebke J; Calsyn D; Shriver K; Saxon A; Kleyn J; Oluoch-Mitchell E;
       Olmstead L; Fisher LD; Krone M; Ashley R; et al; University of
       Washington Center for AIDS and Sexually Transmitted; Diseases, Seattle.
 SO    J Infect Dis. 1994 May;169(5):962-7. Unique Identifier : AIDSLINE
       MED/94223100
 AB    Intravenous drug users (IVDUs) in Seattle (n = 213) were studied to
       identify the prevalence and predominant types of and risk factors for
       human T cell lymphotropic virus (HTLV) infection. Detailed
       questionnaires, serologic screening, and polymerase chain reaction
       analysis (for a subset) were used. Evidence of HTLV infection was found
       in 16.5%, of which 89% were HTLV-II. HTLV infection was significantly
       associated with nonwhite race, older age, more years of intravenous drug
       use, prior use of heroin, history of gonorrhea, history of any sexually
       transmitted disease, hepatitis B virus infection, and antibody to herpes
       simplex virus type 2 (HSV-2). By stepwise logistic regression analysis,
       associations persisted with race, age, hepatitis B markers, and HSV-2.
       Thus, the strong association of HTLV with hepatitis B, a marker for
       injection behavior, and the independent association with HSV-2
       infection, a sexually transmitted pathogen, suggest similarities in the
       epidemiology of HTLV and human immunodeficiency virus infections in
       IVDUs.
 DE    Adult  Female  Human  HTLV-I Infections/COMPLICATIONS/*EPIDEMIOLOGY
       HTLV-II Infections/COMPLICATIONS/*EPIDEMIOLOGY  Male  Middle Age
       Polymerase Chain Reaction  Prevalence  Questionnaires  Regression
       Analysis  Risk Factors  Substance Abuse,
       Intravenous/*COMPLICATIONS/EPIDEMIOLOGY  Support, U.S. Gov't, P.H.S.
       Washington/EPIDEMIOLOGY  JOURNAL ARTICLE

       SOURCE: National Library of Medicine.  NOTICE: This material may be
       protected by Copyright Law (Title 17, U.S.Code).