Document 0091
 DOCN  M9460091
 TI    Zygomycosis and HIV infection.
 DT    9408
 AU    Sanchez MR; Ponge-Wilson I; Moy JA; Rosenthal S; Ronald O. Perelman
       Department of Dermatology, New York University; Medical Center, NY
       10016.
 SO    J Am Acad Dermatol. 1994 May;30(5 Pt 2):904-8. Unique Identifier :
       AIDSLINE MED/94222906
 AB    The severe immunosuppression associated with HIV infection increases
       susceptibility to opportunistic fungi. We describe a primary gangrenous
       cutaneous infection caused by Rhizopus arrhizus in an HIV-infected
       intravenous narcotic user. In addition, we review nine reported cases of
       zygomycosis in HIV-infected patients and discuss the frequency and
       outcome of zygomycosis in HIV infection. Eight of 10 patients were
       intravenous drug users. Cutaneous infection occurred in four patients.
       Another case was associated with drug-induced neutropenia. With
       treatment, 60% of the patients recovered. HIV-induced immunosuppression
       rarely predisposes to zygomycosis except in intravenous drug users or
       persons with other risk factors for this fungal infection.
 DE    Abscess/MICROBIOLOGY  Adult  AIDS-Related Opportunistic
       Infections/*PATHOLOGY  Case Report  Dermatomycoses/*PATHOLOGY  Human
       HIV Infections/*PATHOLOGY  Male  Mucormycosis/*PATHOLOGY  *Rhizopus
       Skin Ulcer/MICROBIOLOGY  JOURNAL ARTICLE  REVIEW  REVIEW OF REPORTED
       CASES

       SOURCE: National Library of Medicine.  NOTICE: This material may be
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