Document 0157
 DOCN  M9460157
 TI    T-cell subsets in acute psychotic schizophrenic patients.
 DT    9408
 AU    Achiron A; Noy S; Pras E; Lereya J; Hermesh H; Laor N; Department of
       Neurology, Beilinson Medical Center, Petah-Tiqva,; Israel.
 SO    Biol Psychiatry. 1994 Jan 1;35(1):27-31. Unique Identifier : AIDSLINE
       MED/94220539
 AB    Two-color flow cytometric analysis was performed on peripheral blood
       lymphocytes of 16 untreated schizophrenic patients during an acute
       psychotic attack and 16 healthy control subjects to evaluate differences
       in T-cell subpopulations. In schizophrenic patients, we observed
       decrease in CD4+ 2H4+ (suppressor-inducer) and CD8+ 2H4+
       (suppressor-effector) T-cell subsets. The selective loss of 2H4+ cell
       markers both on helper and suppressor T cells was not correlated to the
       severity of the acute psychosis. Our results may indicate a mechanism of
       an immune disequilibrium in schizophrenic patients during an acute
       psychotic attack.
 DE    Acute Disease  Adolescence  Adult  CD4-CD8 Ratio  Female  Flow Cytometry
       Human  Leukocyte Count  Male  Middle Age  Reference Values
       Schizophrenia/*IMMUNOLOGY  *Schizophrenic Psychology  Signal Processing,
       Computer-Assisted  T-Lymphocyte Subsets/*IMMUNOLOGY  JOURNAL ARTICLE

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