Document 0165 DOCN M9460165 TI Treatment of infections in the patient with acquired immunodeficiency syndrome. DT 9408 AU Smith GH; College of Pharmacy, University of Arizona, Tucson. SO Arch Intern Med. 1994 May 9;154(9):949-73. Unique Identifier : AIDSLINE MED/94234858 AB Modern technology has led to a contemporary medical practice that must be able to manage a variety of opportunistic infections in the immunocompromised host. The most common causes of immune suppression are immunosuppressive therapy after organ transplantation, granulocytopenia secondary to cancer chemotherapy, and the human immunodeficiency virus (HIV). All of these forms of immunosuppression predispose patients to a wide variety of opportunistic infections caused by reduction in T- and B-cell lymphocyte function as well as depression of neutrophils. However, the acquired immunodeficiency syndrome (AIDS) has presented the clinician with the greatest challenge in this area. Therefore, it is imperative that physicians and other health care professionals have a comprehensive understanding of the recommended therapy as well as the epidemiology, pathogenesis, and diagnosis of the various infections in these patients. DE AIDS-Related Opportunistic Infections/MICROBIOLOGY/PARASITOLOGY/ *THERAPY Bacterial Infections/THERAPY Human Mycoses/THERAPY Parasitic Diseases/THERAPY Support, Non-U.S. Gov't Virus Diseases/THERAPY JOURNAL ARTICLE REVIEW REVIEW, ACADEMIC SOURCE: National Library of Medicine. NOTICE: This material may be protected by Copyright Law (Title 17, U.S.Code).