Document 0169 DOCN M9460169 TI Clinical manifestations of photosensitivity in patients with human immunodeficiency virus infection [editorial] DT 9408 AU Gregory N; DeLeo VA SO Arch Dermatol. 1994 May;130(5):630-3. Unique Identifier : AIDSLINE MED/94234744 AB A number of light-induced pathologic changes in the skin of individuals with HIV infection have been reported in the dermatologic literature. The relationship between HIV and one of these more well-defined types of photosensitivity, PCT, while still uncertain seems definable and related to an infectious origin. The relationship of retrovirus infection and photosensitivities that are of idiopathic origin in HIV-infected individuals, as well as non-infected individuals, is much more conjectural. The association seems, however, to be more frequent than co-incidental, and the link probably resides in the realm of altered immune modulation. Since individuals with HIV frequently require phototherapy, such light-induced problems are likely to become more common. It is important that the dermatologist recognize these relationships. DE Chronic Disease Dermatitis, Photoallergic/COMPLICATIONS Genes, Viral Human Hyperpigmentation/COMPLICATIONS HIV/GENETICS HIV Infections/*COMPLICATIONS Lichenoid Eruptions/COMPLICATIONS Photosensitivity Disorders/*COMPLICATIONS Porphyria, Cutanea Tarda/COMPLICATIONS Ultraviolet Rays EDITORIAL JOURNAL ARTICLE SOURCE: National Library of Medicine. NOTICE: This material may be protected by Copyright Law (Title 17, U.S.Code).