Document 0333 DOCN M9460333 TI The identity of Pneumocystis carinii: not a single protozoan, but a diverse group of exotic fungi. DT 9408 AU Stringer JR; Department of Molecular Genetics, Biochemistry, and Microbiology,; College of Medicine, University of Cincinnati, OH 45267-0524. SO Infect Agents Dis. 1993 Jun;2(3):109-17. Unique Identifier : AIDSLINE MED/94228117 AB Pneumocystosis is an AIDS-associated pneumonia that is characterized by the accumulation of very large numbers of a eucaryotic single-celled organism called Pneumocystis carinii, which has not been cultured. Pneumocystosis also occurs in many other mammalian species, and the rubric P. carinii is currently used to refer to organisms associated with this disease in all host species. This article reviews molecular genetic data establishing that P. carinii is a fungus, that P. carinii in people is not the same organism as P. carinii in rats, and that there may be more than one species of P. carinii, capable of infecting an individual patient. The implications of such genetic diversity for understanding and combating pneumocystosis are discussed. DE Animal Human Nomenclature Pneumocystis carinii/*CLASSIFICATION/GENETICS Rats/MICROBIOLOGY Support, U.S. Gov't, P.H.S. JOURNAL ARTICLE REVIEW REVIEW, TUTORIAL SOURCE: National Library of Medicine. NOTICE: This material may be protected by Copyright Law (Title 17, U.S.Code).