Document 0342
 DOCN  M9460342
 TI    Longitudinal changes in injection behaviors in a cohort of injection
       drug users.
 DT    9408
 AU    Saxon AJ; Calsyn DA; Jackson TR; Seattle Veterans Affairs Medical
       Center, Washington 98108.
 SO    Addiction. 1994 Feb;89(2):191-202. Unique Identifier : AIDSLINE
       MED/94227715
 AB    To determine how the injecting behaviors of injection drug users (IDUs)
       change over time in the context of the epidemic of acquired
       immunodeficiency syndrome (AIDS) and what factors may be associated with
       such changes, a cohort of IDUs (n = 313) initially in treatment provided
       structured interviews regarding drug injecting behaviors. Repeat
       interviews in 18 months assessed behavior change in subjects who could
       be contacted for follow-up (n = 220, 70.3%). The study occurred in a
       state where sterile syringes can be purchased without prescription in
       drug stores. Injection drug use occurred for 180 (81.8%) of the 220
       subjects in the 12 months prior to the initial interview but in only 121
       (55.0%) in the 10 months prior to the follow-up interview (p < 0.0001).
       Similarly, sharing of equipment decreased from 63.1% to 31.8% (p <
       0.0001). Sharing with multiple partners declined from 41.9% to 10.6% (p
       < 0.0001). Factors associated with ongoing risk included use of injected
       and non-injected psychoactive substances, less time in drug dependence
       treatment during follow-up interval, having a sexual partner who was an
       IDU and not using a drug store as the primary source of syringes.
       Factors associated with multiple-partner sharing included use of
       psychoactive substances, younger age and nonwhite race.
 DE    Cohort Studies  Follow-Up Studies  Human  HIV Infections/PREVENTION &
       CONTROL/PSYCHOLOGY/*TRANSMISSION  HIV Seroprevalence/*TRENDS  Knowledge,
       Attitudes, Practice  Longitudinal Studies  Narcotic
       Dependence/EPIDEMIOLOGY/PSYCHOLOGY/REHABILITATION  Needle
       Sharing/ADVERSE EFFECTS/STATISTICS & NUMER DATA  *Psychotropic Drugs
       Sexual Partners/PSYCHOLOGY  *Street Drugs  Substance Abuse,
       Intravenous/*EPIDEMIOLOGY/PSYCHOLOGY/  REHABILITATION  Support, U.S.
       Gov't, Non-P.H.S.  Support, U.S. Gov't, P.H.S.  Washington/EPIDEMIOLOGY
       JOURNAL ARTICLE

       SOURCE: National Library of Medicine.  NOTICE: This material may be
       protected by Copyright Law (Title 17, U.S.Code).