Document 0014
 DOCN  M9470014
 TI    Crohn's ileitis in a patient with longstanding HIV infection.
 DT    9409
 AU    Bernstein BB; Gelb A; Tabanda-Lichauco R; Division of Gastroenterology,
       Beth Israel Medical Center, New; York, N.Y.
 SO    Am J Gastroenterol. 1994 Jun;89(6):937-9. Unique Identifier : AIDSLINE
       MED/94256472
 AB    The differential diagnosis of diarrhea in patients infected with HIV is
       broad, and includes a variety of bacterial, viral, and parasitic
       pathogens, as well as malignancies including lymphoma and Kaposi's
       sarcoma. Idiopathic non-specific inflammatory bowel disease rarely
       occurs in association with HIV infection. A recent case report described
       a patient with longstanding Crohn's disease who experienced remission of
       his bowel disease upon infection with HIV (6). The authors inferred that
       the remission was secondary to a depressed CD4 (T helper) lymphocyte
       count. We report the first case of Crohn's ileitis developing in a
       patient with established HIV infection, depressed CD4 lymphocyte count,
       and no prior history of inflammatory bowel disease. This case raises
       questions about the role of CD4 cells in the pathogenesis of Crohn's
       disease.
 DE    Acquired Immunodeficiency Syndrome/*COMPLICATIONS/IMMUNOLOGY  Case
       Report  Crohn Disease/*COMPLICATIONS/IMMUNOLOGY/PATHOLOGY  Human
       Ileum/PATHOLOGY  Leukocyte Count  Male  Middle Age  T4
       Lymphocytes/IMMUNOLOGY  JOURNAL ARTICLE

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