Document 0051 DOCN M9470051 TI Mucosal origin of AIDS. DT 9409 AU Bourinbaiar AS; Department of Pediatrics, NYU Medical Center, NY 10016. SO Med Hypotheses. 1994 Jan;42(1):43-4. Unique Identifier : AIDSLINE MED/94254744 AB The natural history of AIDS implies sexual and breast-milk transmission of HIV across the mucosal lining of digestive and reproductive organs. Intraepithelial mucosal lymphocytes specialized in handling foods, air-borne, and microbial pathogens crossing the mucosal barrier represent up to 90% of immunocompetent cells in a human body. Enteropathy and respiratory infections, the main symptoms and cause of death in AIDS, are attributed to the failure of mucosal immunity. DE Acquired Immunodeficiency Syndrome/IMMUNOLOGY/*TRANSMISSION Digestive System Genitalia Human Milk, Human/MICROBIOLOGY Mucous Membrane/IMMUNOLOGY/*MICROBIOLOGY JOURNAL ARTICLE SOURCE: National Library of Medicine. NOTICE: This material may be protected by Copyright Law (Title 17, U.S.Code).