Document 0099
 DOCN  M9470099
 TI    Utility of paired blood cultures and smears in diagnosis of disseminated
       Mycobacterium avium complex infections in AIDS patients.
 DT    9409
 AU    Stone BL; Cohn DL; Kane MS; Hildred MV; Wilson ML; Reves RR; Denver
       Disease Control Service, Denver Health and Hospital,; Colorado 80204.
 SO    J Clin Microbiol. 1994 Mar;32(3):841-2. Unique Identifier : AIDSLINE
       MED/94253361
 AB    For 273 patients evaluated for disseminated Mycobacterium avium complex
       infection, a total of 1,047 mycobacterial blood cultures (MBCs) were
       submitted; the M. avium complex was recovered from 140 (13%) of the
       specimens. Results for the paired MBCs were highly concordant: in 392 of
       462 (85%) culture sets, both MBCs were negative, in 53 of 462 (11%)
       sets, both MBCs were positive, and in only 17 of 462 (4%) sets was one
       culture positive and the other negative. Acid-fast smears were done on
       sediments from 671 specimens; smears were positive for 4 of 98 (4%)
       cultures that grew the M. avium complex. A single MBC should be obtained
       and then repeated if negative and disseminated M. avium complex
       infection is still clinically suspected. Use of direct acid-fast smears
       of sediments is not a reliable means of detecting mycobacteremia.
 DE    AIDS-Related Opportunistic Infections/COMPLICATIONS/*DIAGNOSIS/
       MICROBIOLOGY  Bacteremia/*COMPLICATIONS/*DIAGNOSIS/MICROBIOLOGY
       *Bacteriological Techniques/ECONOMICS  Costs and Cost Analysis
       Diagnostic Errors  Human  Mycobacterium avium Complex/ISOLATION & PURIF
       Mycobacterium avium-intracellulare Infection/*COMPLICATIONS/
       *DIAGNOSIS/MICROBIOLOGY  JOURNAL ARTICLE

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