Document 0841
 DOCN  M9480841
 TI    Evaluation of a new HIV-1/HIV-2 assay.
 DT    9410
 AU    Betlach B; Hanson M; Valinsky J; Sacramento Medical Foundation Center
       for Blood Research, CA.
 SO    Abstr Gen Meet Am Soc Microbiol. 1994;94:554 (abstract no. C-363).
       Unique Identifier : AIDSLINE ASM94/94313104
 AB    Three blood donor sites in the United States evaluated a new MicroTrak
       II enzyme immunoassay pending FDA approval for the detection of
       antibodies to HIV-1 and/or HIV-2. It was compared with licensed
       reference assays. Fresh samples from 10,468 volunteer blood donors, and
       417 archival frozen samples positive for HIV-1 antibodies were tested.
       The MicroTrak II assay had a sensitivity of 99.76% on the HIV-1 positive
       samples. One sample that tested negative was collected in 1988, had been
       subjected to several freeze-thaw cycles and was visually cloudy. This
       sample is undergoing further evaluation. The specificity of the blood
       donor samples was 99.86%. TABULAR DATA, SEE ABSTRACT VOLUME. The
       MicroTrak II anti-HIV 1/2 assay has equivalent sensitivity and
       specificity to currently licensed methods except for one tested sample
       undergoing further evaluation.
 DE    Acquired Immunodeficiency Syndrome/*DIAGNOSIS/PREVENTION &  CONTROL
       *Blood Donors  Comparative Study  Human  HIV Antibodies/*BLOOD  HIV
       Seropositivity/*DIAGNOSIS  HIV-1/*ISOLATION & PURIF  HIV-2/*ISOLATION &
       PURIF  Reference Standards  Sensitivity and Specificity  United States
       MEETING ABSTRACT

       SOURCE: National Library of Medicine.  NOTICE: This material may be
       protected by Copyright Law (Title 17, U.S.Code).