Document 0305
 DOCN  M9490305
 TI    Superior sagittal sinus thrombosis in a patient with acquired
       immunodeficiency syndrome.
 DT    9411
 AU    Doberson MJ; Kleinschmidt-DeMasters BK; Department of Pathology,
       University of Colorado Health Sciences; Center, Denver 80262.
 SO    Arch Pathol Lab Med. 1994 Aug;118(8):844-6. Unique Identifier : AIDSLINE
       MED/94338265
 AB    A 41-year-old man with acquired immunodeficiency syndrome was admitted
       to the hospital because of a recent onset of disorientation and memory
       loss. He developed focal neurologic signs on hospital day 4, and a
       computed tomographic scan of his head showed a right medial temporal
       lobe hyperdensity. Before diagnosis could be made or treatment started,
       the patient was unexpectedly found dead on hospital day 14. At autopsy,
       a primary central nervous system B-cell immunoblastic lymphoma was found
       involving both hippocampi and other periventricular areas. Associated
       angiodestruction and necrosis with local vascular thrombosis were seen.
       In addition, there was extensive, partial thrombosis of the superior
       sagittal sinus and distal superficial cortical veins unassociated with
       cerebral hemorrhage or infarction, lymphoma, or involvement with
       opportunistic organisms. Retrospective review of radiographic studies
       demonstrated the classic empty delta sign. To our knowledge, cerebral
       venous and dural sinus thrombosis has not been well documented in
       patients with the acquired immunodeficiency syndrome. Because the dural
       venous sinuses are not routinely examined at autopsy in many
       institutions, cerebral venous/dural sinus thrombosis in patients with
       the acquired immunodeficiency syndrome may be more frequent than is
       presently recognized.
 DE    Acquired Immunodeficiency Syndrome/*COMPLICATIONS  Adult  Case Report
       Central Nervous System Neoplasms/COMPLICATIONS  Human  Lymphoma,
       B-Cell/COMPLICATIONS  Lymphoma, Lymphoblastic/COMPLICATIONS  Magnetic
       Resonance Imaging  Male  Sinus
       Thrombosis/*COMPLICATIONS/DIAGNOSIS/PATHOLOGY  JOURNAL ARTICLE

       SOURCE: National Library of Medicine.  NOTICE: This material may be
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