Document 0315
 DOCN  M9490315
 TI    Characteristics of cervical intraepithelial neoplasia in women infected
       with the human immunodeficiency virus.
 DT    9411
 AU    Fruchter RG; Maiman M; Sillman FH; Camilien L; Webber CA; Kim DS;
       Department of Obstetrics and Gynecology, State University of New; York
       Health Science Center at Brooklyn 11203.
 SO    Am J Obstet Gynecol. 1994 Aug;171(2):531-7. Unique Identifier : AIDSLINE
       MED/94337841
 AB    OBJECTIVE: Our purpose was to compare characteristics of cervical
       intraepithelial neoplasia in relation to human immunodeficiency virus
       infection among women referred to a public hospital colposcopy clinic
       with Papanicolaou smears showing cervical intraepithelial neoplasia.
       STUDY DESIGN: An evaluation of cervical intraepithelial neoplasia
       severity, lesion size, and vulvovaginal lesions with respect to human
       immunodeficiency virus status was performed. RESULTS: (1) Human
       immunodeficiency virus prevalence in 482 women with cytologic
       characteristics of cervical intraepithelial neoplasia was 13%. (2) In
       human immunodeficiency virus-infected patients, Papanicolaou smears were
       less adequate for evaluation and correlated less well with histologic
       findings than in uninfected patients (p < 0.05). (3) Human
       immunodeficiency virus-infected patients (n = 47) had more advanced
       cervical intraepithelial neoplasia, larger cervical lesions, and more
       associated vulvovaginal lesions than human immunodeficiency
       virus-negative patients (n = 161). In human immunodeficiency
       virus-positive women, the severity of cervical intraepithelial neoplasia
       was not associated with age, whereas in human immunodeficiency
       virus-negative women, increasing severity was significantly associated
       with increasing age. CONCLUSION: High rates of human immunodeficiency
       virus infection in inner-city colposcopy services and high-grade,
       extensive cervical lesions in infected women warrant special attention.
 DE    Adult  Cervical Intraepithelial Neoplasia/COMPLICATIONS/*PATHOLOGY
       Cervix Neoplasms/COMPLICATIONS/*PATHOLOGY  Cross-Sectional Studies
       Female  Human  HIV Infections/*COMPLICATIONS  Support, Non-U.S. Gov't
       JOURNAL ARTICLE

       SOURCE: National Library of Medicine.  NOTICE: This material may be
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