Document 0326
 DOCN  M9490326
 TI    A study of the CD4: CD8 ratio in peripheral T lymphocytes of rural Papua
       New Guineans: a reduced ratio assessed with regard to infectious agents.
 DT    9411
 AU    Turner PF; Anton Breinl Centre for Tropical Health and Medicine, James
       Cook; University of North Queensland, Townsville, Australia.
 SO    P N G Med J. 1993 Sep;36(3):210-4. Unique Identifier : AIDSLINE
       MED/94337536
 AB    The CD4:CD8 ratio in peripheral T lymphocytes was determined in 123
       Papua New Guineans aged over 5 years from Rumginae, a rural area of the
       Western Province. 18 people had a ratio less than 1.0. No antibody
       response to human immunodeficiency virus 1 (HIV 1) was found within the
       group. Hepatitis B surface antigen was more commonly associated with a
       CD4:CD8 ratio less than 1.0 than were microfilaraemia or a positive
       Mantoux test. Hepatitis B infection may be one of the causes of the
       CD4:CD8 ratio reduction within the community. Irrespective of the cause,
       other studies in Papua New Guinea have shown that a CD4:CD8 ratio less
       than 1.0 may result more from an increase in the CD8 cell count than a
       reduction in the CD4 cell count.
 DE    Adolescence  Adult  Age Distribution  Aged  Animal  Child  Child,
       Preschool  *CD4-CD8 Ratio  Elephantiasis,
       Filarial/*BLOOD/EPIDEMIOLOGY/IMMUNOLOGY  Female  Hepatitis
       B/*BLOOD/EPIDEMIOLOGY/IMMUNOLOGY  Hepatitis B Surface Antigens/BLOOD
       Human  HIV Infections/*BLOOD/EPIDEMIOLOGY/IMMUNOLOGY  *HIV-1  Male
       Middle Age  Papua New Guinea/EPIDEMIOLOGY  *Population Surveillance
       Prevalence  *Rural Population  Seroepidemiologic Methods  Tuberculin
       Test  Tuberculosis/*BLOOD/EPIDEMIOLOGY/IMMUNOLOGY  *Wuchereria bancrofti
       JOURNAL ARTICLE

       SOURCE: National Library of Medicine.  NOTICE: This material may be
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