Document 0329
 DOCN  M9490329
 TI    HIV serosurveillance in Papua New Guinea.
 DT    9411
 AU    O'Leary MJ; van der Meijden WI; Malau C; Delamare O; Pyakalyia T; World
       Health Organization, Department of Health, Port Moresby,; Papua New
       Guinea.
 SO    P N G Med J. 1993 Sep;36(3):187-91. Unique Identifier : AIDSLINE
       MED/94337533
 AB    To determine human immunodeficiency virus-1 (HIV-1) prevalence in low-
       and high-risk populations in Papua New Guinea (PNG), anonymous unlinked
       serosurveillance was conducted in government-administered antenatal and
       sexually transmitted disease (STD) clinics at six sites beginning in
       June 1989. Although 3 of 1233 samples were HIV positive in a pilot
       study, none of 7948 samples was HIV positive during the first full year
       of serosurveillance (June 1989--May 1990). HIV-infected people are also
       identified in PNG through clinical diagnostic testing. Although
       underreporting is probably substantial, 45 HIV-infected people had been
       identified in PNG (population 3.6 million) through diagnostic testing
       between 1987 and the end of the first serosurveillance year (May 1990).
       In view of the steadily emerging clinical problem of acquired immune
       deficiency syndrome (AIDS) in PNG, the negative results of
       serosurveillance required explanation. Three possibilities are proposed:
       1) the sample size chosen could fail to detect a case 5% (or more) of
       the time under the likely conditions of this survey; 2) the populations
       chosen for surveillance may not, yet, be those in which HIV is
       circulating at this early stage of the epidemic in PNG; and 3)
       laboratory error could account for some false negative results. The
       first two of these, alone or in combination, are most likely. Limited
       surveillance continued in PNG in 1991 and 1992. By June of 1992, 5 of an
       additional 6035 serosurveillance samples had tested positive. All 5 were
       among 2000 samples from a single site, the Port Moresby STD
       Clinic.(ABSTRACT TRUNCATED AT 250 WORDS)
 DE    Adult  Bias (Epidemiology)  Female  Human  HIV
       Infections/BLOOD/COMPLICATIONS/*EPIDEMIOLOGY  *HIV Seroprevalence
       *HIV-1  Infant, Newborn  Male  Papua New Guinea/EPIDEMIOLOGY  Pilot
       Projects  *Population Surveillance  Prevalence  Risk Factors
       Seroepidemiologic Methods  Sexually Transmitted
       Diseases/COMPLICATIONS/EPIDEMIOLOGY  Support, Non-U.S. Gov't  JOURNAL
       ARTICLE

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