Document 0341 DOCN M9490341 TI [Risk of nosocomial Pneumocystis carinii pneumonia in immunosuppressed patients non-infected by human immunodeficiency viruses] DT 9411 AU Mounib B; Cabane J; Blum L; Picard O; Wattiaux MJ; Imbert JC; Service de medecine interne 3, hopital Saint-Antoine, Paris,; France. SO Rev Med Interne. 1994 Feb;15(2):95-100. Unique Identifier : AIDSLINE MED/94337085 AB We report four cases of Pneumocystis carinii pneumonia (PCP) in Human Immunodeficiency Virus (HIV)-seronegative patients. Two of them had been hospitalized for polymyositis treatment near AIDS patients, respectively 1 and 4 months before PCP. The two others suffered from localized cancer. Their evolution was complicated by respiratory distress and death in two of them. A telephone survey among 19 hospital units yielded nine cases of similar patients. They were only observed in wards caring for AIDS patients at the same time, thus raising the question of a possible nosocomial transmission of PCP between AIDS patients and immunocompromised HIV-seronegative patients. This adds to the growing concern for hospital-acquired infections, including resistant tuberculosis and other opportunistic pathogens. We propose some practical measures to limit this risk by simple means such as no-contact between at-risk populations, enhanced disinfection procedures of the rooms and masking of the coughing PCP patients. DE Aged Aged, 80 and over Case Report *Cross Infection English Abstract Female Hospitals, Public Human *HIV Seronegativity *Immunocompromised Host Male Middle Age Paris/EPIDEMIOLOGY Pneumonia, Pneumocystis carinii/*EPIDEMIOLOGY Risk Factors JOURNAL ARTICLE REVIEW REVIEW, TUTORIAL SOURCE: National Library of Medicine. NOTICE: This material may be protected by Copyright Law (Title 17, U.S.Code).