Document 0469 DOCN M9490469 TI Inhibitors of HIV-1 transcription. DT 9411 AU Li CJ; Dezube BJ; Biswas DK; Ahlers CM; Pardee AB; Divn of Cell Growth and Regulation, Dana-Farber Cancer Institute,; Boston, MA 02115. SO Trends Microbiol. 1994 May;2(5):164-9. Unique Identifier : AIDSLINE MED/94332441 AB No curative drug against HIV has yet been found, despite enormous efforts aimed at reverse transcriptase and a variety of other targets. The long terminal repeat (LTR) of HIV-1 has recently become a promising site for antiviral action. This article briefly summarizes information on the nature of this target and potential anti-LTR expression drugs. DE Acquired Immunodeficiency Syndrome/*DRUG THERAPY Antiviral Agents/*PHARMACOLOGY/THERAPEUTIC USE Base Sequence Human HIV Long Terminal Repeat/*GENETICS HIV-1/*DRUG EFFECTS/GENETICS Models, Biological Molecular Sequence Data Support, Non-U.S. Gov't Support, U.S. Gov't, P.H.S. Trans-Activation (Genetics)/DRUG EFFECTS Transcription, Genetic/*DRUG EFFECTS JOURNAL ARTICLE REVIEW REVIEW, TUTORIAL SOURCE: National Library of Medicine. NOTICE: This material may be protected by Copyright Law (Title 17, U.S.Code).