Document 0478
 DOCN  M9490478
 TI    [Neuroradiological findings in perinatally HIV-infected children]
 DT    9411
 AU    Spreer J; Enenkel-Stoodt S; Funk M; Fiedler A; de Simone A; Hacker H;
       Radiologische Abteilung, Universitatsklinik Koln.
 SO    Rofo Fortschr Geb Rontgenstr Neuen Bildgeb Verfahr. 1994
       Aug;161(2):106-12. Unique Identifier : AIDSLINE MED/94331627
 AB    The neuroradiological studies (CT, MRI, angiography) in 21 children with
       perinatal HIV infection were reviewed retrospectively. No patient showed
       an intracranial mass lesion; after intravenous contrast medium
       application there was no case with disturbed blood-brain barrier. Common
       non-specific findings were atrophy and delayed myelination. In 7 cases
       atrophy was combined with multifocal nearly symmetric white matter
       lesions, which characteristically spared the U-fibres. Further findings
       included an intramedullary ring-shaped structure in the cervical cord,
       an AIDS-associated vasculopathy and symmetric calcifications in the
       basal ganglia. The spectrum of neuroradiological findings in paediatric
       AIDS patients differs from that in adults. Knowledge of these
       age-specific findings is important because the number of HIV-infected
       children is rising.
 DE    Age Factors  Atrophy  Basal Ganglia/PATHOLOGY  Brain/PATHOLOGY  Central
       Nervous System/*RADIOGRAPHY  Cerebral Angiography  Child  Child,
       Preschool  English Abstract  Female  Human  HIV
       Infections/DIAGNOSIS/*RADIOGRAPHY  Infant  Magnetic Resonance Imaging
       Male  Retrospective Studies  Spinal Cord/PATHOLOGY  Tomography, X-Ray
       Computed  JOURNAL ARTICLE

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