Document 0486
 DOCN  M9490486
 TI    Nontyphoidal salmonellal septicemia in Gabonese children infected with
       Schistosoma intercalatum.
 DT    9411
 AU    Gendrel D; Kombila M; Beaudoin-Leblevec G; Richard-Lenoble D; Hopital
       Saint-Vincent-de-Paul, Paris, France.
 SO    Clin Infect Dis. 1994 Jan;18(1):103-5. Unique Identifier : AIDSLINE
       MED/94331487
 AB    Relapses of enteric fever induced by Schistosoma intercalatum have been
       observed to occur in central Africa. In Libreville, Gabon, 70 children
       (ages, 2.1-15.9 years) who were seronegative for human immunodeficiency
       virus and were hospitalized for septicemic salmonellosis underwent
       rectal biopsy for diagnosis of S. intercalatum infection. A nontyphoidal
       Salmonella species was isolated from 53 of the 70 patients: Salmonella
       typhimurium in 14 cases; Salmonella enteritidis in 7 cases; Salmonella
       galiema in 4 cases; Salmonella arizonae in 3 cases; and other species in
       25 cases. Schistosomal eggs were present in the rectal mucosa of 48
       (90.6%) of these 53 patients, in 11 (64.7%) of 17 patients with
       septicemia due to Salmonella typhi or Salmonella paratyphi, and in 21
       (38.2%; P < .001) of 55 controls. Clinical symptoms were not different
       among patients coinfected with S. intercalatum and nontyphoidal
       Salmonella vs. those with enteric fever. Treatment with antibiotics
       induced apyrexia only after administration of antiparasitic therapy in
       30 patients. These data strongly suggest interactions between S.
       intercalatum and Salmonella in infected children with clinically severe
       nontyphoidal salmonellal septicemia.
 DE    Adolescence  Child  Child, Preschool  Chloramphenicol/THERAPEUTIC USE
       Female  Gabon  Human  Male  Parasite Egg Count  Prospective Studies
       Salmonella Infections/*COMPLICATIONS/DRUG THERAPY/MICROBIOLOGY
       Schistosomiasis/*COMPLICATIONS/DIAGNOSIS  Septicemia/*COMPLICATIONS/DRUG
       THERAPY/MICROBIOLOGY  JOURNAL ARTICLE

       SOURCE: National Library of Medicine.  NOTICE: This material may be
       protected by Copyright Law (Title 17, U.S.Code).