Document 0091
 DOCN  M94A0091
 TI    Mucocutaneous diseases in drug addicts with or without HIV infection. A
       case-control study.
 DT    9412
 AU    Gaeta GB; Maisto A; Sichenze C; Satriano RA; Sardaro C; Giusti G;
       Clinica Malattie Infettive, Seconda Universita, Naples, Italy.
 SO    Infection. 1994 Mar-Apr;22(2):77-80. Unique Identifier : AIDSLINE
       MED/94350510
 AB    A case-control study was performed to evaluate the prevalence of
       mucocutaneous diseases in 106 male drug addicts (age 21-38 years) with
       or without HIV infection. A mucocutaneous disease was recorded in ten
       out of 64 HIV-negative and in 20 of 42 HIV-positive patients (OR = 4.9;
       p < 0.01). Some mucocutaneous diseases were present in similar
       proportions in both groups (i.e. fungal skin lesions), while others were
       typically present only in HIV-positive patients. Stratification for
       possible confounding factors, such as years of drug addiction and number
       of sexual partners, confirmed that HIV infection is the main risk factor
       for mucocutaneous disease. Stratification according to the number of
       CD4-positive cells showed that the more advanced the HIV disease, the
       more frequently mucocutaneous disease was present (p = 0.02). The study
       demonstrates that many, but not all, mucocutaneous diseases are
       associated with HIV infection.
 DE    Adult  Case-Control Studies  Confounding Factors (Epidemiology)  Human
       HIV Infections/COMPLICATIONS/*EPIDEMIOLOGY  Male  Mucous Membrane  Odds
       Ratio  *Population Surveillance  Prevalence  Risk Factors  Sexual
       Partners  Skin Diseases/COMPLICATIONS/*EPIDEMIOLOGY  Substance
       Dependence/*COMPLICATIONS  Support, Non-U.S. Gov't  JOURNAL ARTICLE

       SOURCE: National Library of Medicine.  NOTICE: This material may be
       protected by Copyright Law (Title 17, U.S.Code).