Document 0092
 DOCN  M94A0092
 TI    Hepatitis C virus infection in a sexually active inner city population.
       The potential for heterosexual transmission.
 DT    9412
 AU    Daikos GL; Lai S; Fischl MA; Dept. of Medicine, University of Miami
       School of Medicine,; Florida 33101.
 SO    Infection. 1994 Mar-Apr;22(2):72-6. Unique Identifier : AIDSLINE
       MED/94350509
 AB    The prevalence of hepatitis C virus (HCV) infection and associated risk
       factors in an inner city sexually active heterosexual population
       participating in a prospective study for the evaluation of heterosexual
       transmission of human immunodeficiency virus type-1 (HIV-1) were
       examined. Individuals with prior history of injection drug use or
       receipt of blood products were excluded from the study. Of 571
       participants, 25 (4.4%) were seropositive for HCV, 39 (7%) for HIV, and
       125 (22%) for hepatitis B virus (HBV). Multivariate analysis revealed
       that those with more than ten heterosexual partners in the past 5 years
       (OR = 3.7; 95% CI = 1.3, 10.2; P = 0.01), engaging in sexual practices
       more than once per week (OR = 3.3; 95% CI = 1.1, 10.1; P = 0.04), with
       antibody to hepatitis B core (HBc) antigen (OR = 2.9; 95% CI = 1.1, 7.4;
       P = 0.03), and antibody to HIV-1 (OR = 5.8; 95% CI = 1.9; 17.6; P =
       0.002) were independently associated with HCV infection. These findings
       suggest that heterosexual transmission of HCV may occur in an inner city
       sexually active heterosexual population.
 DE    Adolescence  Adult  Aged  Female  Florida/EPIDEMIOLOGY  Hepatitis
       B/COMPLICATIONS/*EPIDEMIOLOGY/TRANSMISSION  Hepatitis
       C/COMPLICATIONS/*EPIDEMIOLOGY/*TRANSMISSION  Human  HIV
       Infections/COMPLICATIONS/*EPIDEMIOLOGY/TRANSMISSION  *HIV-1  Male
       Middle Age  Multivariate Analysis  Odds Ratio  *Population Surveillance
       Prevalence  Prospective Studies  Risk Factors  *Sex Behavior  Sexual
       Partners  Support, U.S. Gov't, P.H.S.  *Urban Population  JOURNAL
       ARTICLE

       SOURCE: National Library of Medicine.  NOTICE: This material may be
       protected by Copyright Law (Title 17, U.S.Code).