Document 0120
 DOCN  M94A0120
 TI    [Measurement of T cell subsets in bronchoalveolar lavage fluid for
       diagnosis of pulmonary sarcoidosis]
 DT    9412
 AU    He QY; Kitamura S; Ishii Y; Department of Pulmonary Medicine, People's
       Hospital, Beijing; Medical University.
 SO    Chung Hua I Hsueh Tsa Chih. 1994 Feb;74(2):87-9, 126-7. Unique
       Identifier : AIDSLINE MED/94349154
 AB    Pulmonary sarcoidosis is characterized by the accumulation in the lower
       respiratory tract of large numbers of activated CD4 T cells and elevated
       ratio of CD4/CD8 in bronchoalveolar lavage fluid (BALF). To study the
       value of CD4/CD8 ratio in BALF in the diagnosis of pulmonary
       sarcoidosis, we measured T cell subsets in BALF of patients with
       pulmonary sarcoidosis. The CD4/CD8 ratio in the patients (7.5 +/- 4.3)
       was significantly higher than that of the controls (2.1 +/- 0.7). The
       sensitivity and specificity of CD4/CD8 ratio in BALF for the diagnosis
       of sarcoidosis were 86% and 100%, respectively. We found that the
       CD4/CD8 ratio in BALF plays an important role in the diagnosis of
       pulmonary sarcoidosis. The analysis of CD4 in BALF may be useful in
       assessing the activity of sarcoidosis. The measurement of the CD4/CD8
       ratio may be used to determine prognosis of pulmonary sarcoidosis.
 DE    Adult  Bronchoalveolar Lavage Fluid/*IMMUNOLOGY  *CD4-CD8 Ratio
       Diagnosis, Differential  English Abstract  Female  Human  Male
       Sarcoidosis, Pulmonary/*DIAGNOSIS/IMMUNOLOGY  *T-Lymphocyte Subsets
       JOURNAL ARTICLE

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