Document 0155
 DOCN  M94A0155
 TI    Viral infection including HIV and AIDS.
 DT    9412
 AU    Naides SJ; Department of Internal Medicine, University of Iowa College
       of; Medicine, Iowa City 52242.
 SO    Curr Opin Rheumatol. 1994 Jul;6(4):423-8. Unique Identifier : AIDSLINE
       MED/94347573
 AB    Viruses have long been considered candidates for infectious etiologic
       agents or cofactors in the development of rheumatic diseases. The
       current epidemic of HIV infection and the recognition of emerging
       viruses has focused interest on the possible role of viruses in
       pathogenesis of diseases without defined etiology. Over the past year,
       the role of parvovirus B19 in chronic arthropathy was further defined.
       Additional data added to our understanding of the mechanisms by which
       rubella virus may cause chronic arthritis. We were reminded of the
       potential the togaviruses have to cause epidemics of febrile arthritis.
       The developing story of hepatitis C virus in essential mixed
       cryoglobulinemia encourages us to explore strategies for specific
       antiviral therapies. The members of the herpesvirus family came under
       scrutiny for their role in Sjogren's syndrome. The retroviruses continue
       to attract attention because of rheumatic disease syndromes in AIDS
       patients and the suggestion that still undefined retroviruses may play
       an etiologic role in rheumatoid arthritis. This review highlights
       efforts made in the past year to elucidate the role of viral infection
       in rheumatologic disease.
 DE    Arthritis, Infectious/EPIDEMIOLOGY/*MICROBIOLOGY  Hepatitis
       C/COMPLICATIONS  Herpesviridae Infections/COMPLICATIONS  Human
       Parvoviridae Infections/COMPLICATIONS  Retroviridae
       Infections/COMPLICATIONS  Togaviridae Infections/COMPLICATIONS  JOURNAL
       ARTICLE  REVIEW  REVIEW, TUTORIAL

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