Document 0200
 DOCN  M94A0200
 TI    Retinochoroiditis in the acquired immune deficiency syndrome. Findings
       in consecutive post-mortem examinations.
 DT    9412
 AU    Seregard S; Ophthalmic Pathology and Oncology Service, St Erik's Eye;
       Hospital, Stockholm, Sweden.
 SO    Acta Ophthalmol (Copenh). 1994 Apr;72(2):223-8. Unique Identifier :
       AIDSLINE MED/94360747
 AB    A number of opportunistic agents may cause retinitis or
       retinochoroiditis in patients with the acquired immunodeficiency
       syndrome. Minimal consecutive data is available on the
       histopathologically confirmed prevalence of these ocular infections. A
       total of 48 consecutive patients with acquired immunodeficiency
       syndrome-related death underwent autopsy and had their eyes submitted
       for histopathological examination. Conventional light microscopy
       combined with immunohistochemistry revealed cytomegalovirus retinitis in
       15 patients, toxoplasma gonddi retinochoroiditis in 3 patients and
       mycobacterial choroiditis in one individual with some infections being
       coexistent. Clinical examination prior to death was highly accurate in
       detecting cytomegalovirus retinitis, but failed to determine all
       non-cytomegalovirus causes of retinochoroiditis. Ten of 15 patients with
       cytomegalovirus retinitis had associated non-cular cytomegalovirus
       infections, most often in the brain and adrenals. After clinical
       detection of cytomegalovirus retinitis the median survival time was 5.5
       months, not adversely affected by additional non-ocular cytomegalovirus
       infection.
 DE    Adult  Aged  Aged, 80 and over  AIDS-Related Opportunistic
       Infections/*PATHOLOGY  Chorioretinitis/MICROBIOLOGY/*PATHOLOGY
       Cytomegalovirus Retinitis/PATHOLOGY  Eye Infections/*PATHOLOGY  Female
       Human  *HIV-1  Male  Middle Age  Mycobacterium avium-intracellulare
       Infection/PATHOLOGY  Prevalence  Support, Non-U.S. Gov't  Toxoplasmosis,
       Ocular/PATHOLOGY  JOURNAL ARTICLE

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