Document 0276
 DOCN  M94A0276
 TI    The AIDS epidemic.
 DT    9412
 AU    Conant MA; Department of Dermatology, University of California, San;
       Francisco.
 SO    J Am Acad Dermatol. 1994 Sep;31(3 Pt 2):S47-50. Unique Identifier :
       AIDSLINE MED/94358248
 AB    The nature of the clinical presentation of HIV infection continues to
       evolve over time. New cutaneous (e.g., seborrheic dermatitis,
       onychomycosis, and tinea pedis) and systemic (e.g., Aspergillus
       fumigatus and Penicillium marneffei) opportunistic fungal infections can
       now be added to the classic clinical markers for progressive HIV
       infection, such as Kaposi's sarcoma, Pneumocystis carinii pneumonia,
       Mycobacterium avium intercellulare infections, and cryptococcal
       meningitis. The fact that the appearance of many of these fungal
       diseases is directly correlated with the patient's CD4 cell count is a
       valuable tool for ongoing clinical evaluation. Although systemic
       manifestations characterize a progression from asymptomatic HIV
       infection to AIDS, many of the signs of disease progression are
       cutaneous. Prophylaxis against many of the potentially life-threatening
       systemic opportunistic infections associated with HIV positivity has had
       a positive impact on the life expectancy of patients with AIDS.
 DE    Acquired Immunodeficiency Syndrome/COMPLICATIONS/DRUG THERAPY/
       *EPIDEMIOLOGY/IMMUNOLOGY  Antifungal Agents/THERAPEUTIC USE
       AIDS-Related Opportunistic Infections/COMPLICATIONS/DRUG THERAPY/
       *EPIDEMIOLOGY  Dermatomycoses/COMPLICATIONS/DRUG THERAPY/*EPIDEMIOLOGY/
       IMMUNOLOGY  Dermatophytes/PATHOGENICITY
       Eosinophilia/COMPLICATIONS/*EPIDEMIOLOGY/IMMUNOLOGY
       Folliculitis/COMPLICATIONS/*EPIDEMIOLOGY/IMMUNOLOGY  Human  Incidence
       Leukocyte Count  T4 Lymphocytes/IMMUNOLOGY  JOURNAL ARTICLE  REVIEW
       REVIEW, TUTORIAL

       SOURCE: National Library of Medicine.  NOTICE: This material may be
       protected by Copyright Law (Title 17, U.S.Code).