Document 0315
 DOCN  M94A0315
 TI    Endogenous nonecotropic proviruses mapped with oligonucleotide probes
       from the long terminal repeat region.
 DT    9412
 AU    Frankel WN; Coffin JM; Jackson Laboratory, Bar Harbor, Maine 04609.
 SO    Mamm Genome. 1994 May;5(5):275-81. Unique Identifier : AIDSLINE
       MED/94355770
 AB    We characterized endogenous proviruses in C57BL/6J, DBA/2J, and C3H/HeJ
       mouse strains with oligonucleotide probes derived from long terminal
       repeat (LTR) sequences of three classes of nonecotropic murine leukemia
       virus. The segregation of proviral-host DNA junction fragments was
       followed in BXH and BXD recombinant inbred (RI) strain sets, and most
       fragments mapped readily to defined chromosomal regions. Most of the LTR
       fragments appear to correspond to proviruses mapped previously with
       oligonucleotide env region probes of the same viral class. At least 22
       elements represent new proviral loci, no more than half of which may be
       solo LTRs, and an additional six may correspond to proviruses identified
       previously with less specific hybridization probes. Together with
       proviruses identified previously with env probes, the LTR probe-reactive
       elements represent the majority of endogenous murine leukemia proviruses
       in the mouse genome.
 DE    Animal  Base Sequence  Comparative Study  DNA, Viral/*GENETICS  Genes,
       env  Leukemia Viruses, Murine/*GENETICS  Mice  Mice, Inbred
       C3H/GENETICS/*MICROBIOLOGY  Mice, Inbred C57BL/GENETICS/*MICROBIOLOGY
       Mice, Inbred DBA/GENETICS/*MICROBIOLOGY  Molecular Sequence Data
       *Oligonucleotide Probes  Proviruses/*GENETICS  *Repetitive Sequences,
       Nucleic Acid  Support, U.S. Gov't, P.H.S.  JOURNAL ARTICLE

       SOURCE: National Library of Medicine.  NOTICE: This material may be
       protected by Copyright Law (Title 17, U.S.Code).