Document 0338
 DOCN  M94A0338
 TI    An electron-lucent region within the virion distinguishes HIV-1 from
       HIV-2 and simian immunodeficiency virus.
 DT    9412
 AU    Yu QC; Matsuda Z; Yu X; Ito S; Essex M; Lee TH; Department of Cancer
       Biology, Harvard School of Public Health,; Boston, Massachusetts 02115.
 SO    AIDS Res Hum Retroviruses. 1994 Jun;10(6):757-61. Unique Identifier :
       AIDSLINE MED/94355123
 AB    Ultrastructural comparisons of immature or budding particles of human
       immunodeficiency virus (HIV) types 1 and 2 and simian immunodeficiency
       virus of macaques (SIVmac) revealed no significant difference between
       these genetically distinct, but related, viruses. However, a region
       encompassing the core of mature HIV-1 virions was found to be more
       electron lucent than that observed in HIV-2 and SIVmac. This
       ultrastructural distinction cannot be attributed to HIV-1-specific vpu,
       HIV-2/SIV-specific vpx, or virion-associated vpr gene products.
 DE    Comparative Study  HIV-1/*ULTRASTRUCTURE  HIV-2/*ULTRASTRUCTURE
       Microscopy, Electron  Support, U.S. Gov't, Non-P.H.S.  Support, U.S.
       Gov't, P.H.S.  SIV/*ULTRASTRUCTURE  JOURNAL ARTICLE

       SOURCE: National Library of Medicine.  NOTICE: This material may be
       protected by Copyright Law (Title 17, U.S.Code).