Document 0344
 DOCN  M94A0344
 TI    Albuminuria in HIV-infected patients.
 DT    9412
 AU    Busch HW; Riechmann S; Heyen P; Heidenreich S; Kaufmann CC; Rahn KH;
       Zidek W; Medizinische Poliklinik, Westfaelischen Wilhelms Universitaet;
       Muenster, Germany.
 SO    AIDS Res Hum Retroviruses. 1994 Jun;10(6):717-20. Unique Identifier :
       AIDSLINE MED/94355117
 AB    Albumin excretion, Analysis of urinary proteins by polyacrylamide gel
       electrophoresis (PAGE), and clinical evaluation were performed in 90
       HIV-infected patients to assess subclinical renal involvement in HIV
       infection. Thirteen percent of all patients showed an albumin excretion
       > 20 mg/liter. Seven of four homosexual patients had albuminuria.
       Albuminuria occurred exclusively with T4 cell counts below 200/mm3.
       Polyacrylamide gel electrophoresis indicated glomerular lesions and
       showed no tubular proteinuria in patients with increased albumin
       excretion. It is concluded that subclinical renal involvement is not
       uncommon in HIV infection with T4 cell counts > 200/mm3. HIV-associated
       nephropathy and heroin-associated nephropathy may not be the main causes
       of renal involvement. In some cases, opportunistic viral infections may
       be the cause of microalbuminuria.
 DE    Adolescence  Adult  Albuminuria/*COMPLICATIONS/URINE  Caucasoid Race
       Female  Human  HIV Infections/*COMPLICATIONS
       Kidney/*PHYSIOPATHOLOGY/ULTRASONOGRAPHY  Male  Middle Age  T4
       Lymphocytes  JOURNAL ARTICLE

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