Document 0581
 DOCN  M94A0581
 TI    Pseudopancreatitis in HIV disease.
 DT    9412
 AU    Parkin D; Edwards R; Department of HIV Medicine, Royal North Shore
       Hospital, St; Leonards, NSW.
 SO    Annu Conf Australas Soc HIV Med. 1993 Oct 28-30;5:96 (poster no. 43).
       Unique Identifier : AIDSLINE ASHM5/94349074
 AB    We report a case of hyperamylasemia in a 39 year old AIDS patient. He
       presented in May 1992 with Pneumocystis carinii pneumonia and was
       subsequently found to be HIV antibody positive. His CD4 Count was 32. On
       recovery AZT 600mg a day and Bactrim were commenced. In November 1992
       CMV retinitis was diagnosed and Ganciclovir was commenced.
       Antiretroviral therapy was changed to ddl in November 1992. During April
       1993 the patient complained of increasing abdominal discomfort and
       nausea. From February to April 1993 a slowly progressive rise in serum
       amylase was noted, attributed to pancreatitis, and ddl was ceased. In
       May 1993 the patient complained of xerostomia and bilateral parotid
       swelling was noted. The diagnosis of bilateral parotitis was made. A
       salivary gland nuclear medicine study confirmed bilateral parotid
       enlargement. Fractionation of the amylase in early May revealed 85% from
       the salivary glands, 15% from the pancreas. With conservative management
       the parotitis resolved and the serum amylase returned to near normal
       levels. This case serves to highlight that salivary gland dysfunction
       should be considered as a cause of hyperamylasemia in HIV/AIDS patients.
 DE    Acquired Immunodeficiency Syndrome/*DRUG THERAPY/ENZYMOLOGY  Adult
       Amylases/*BLOOD  AIDS-Related Opportunistic Infections/*DRUG
       THERAPY/ENZYMOLOGY  Case Report  Diagnosis, Differential  Human  Male
       Pancreatitis/*CHEMICALLY INDUCED/ENZYMOLOGY  Parotitis/*CHEMICALLY
       INDUCED/ENZYMOLOGY  Saliva/ENZYMOLOGY  MEETING ABSTRACT

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