Document 0666 DOCN M94A0666 TI Depressive pseudodementia. V. Organic cerebral disease. DT 9412 AU Cockram AM; Judd FK; Mijch AM; Fairfield Hospital, Melbourne. SO Annu Conf Australas Soc HIV Med. 1993 Oct 28-30;5:50 (abstract no. TP3). Unique Identifier : AIDSLINE ASHM5/94348989 AB A 30 year homosexual man, was referred for assessment of depressed mood. He had recently been an inpatient for treatment of Mycobacterium avium bacteremia, but had responded well to treatment and had returned to full time employment. He described low mood of several months duration, anxiety, sleep disturbance, poor appetite and loss of weight. He had continued to work, but had noted poor concentration, memory impairment and decreased work performance. A diagnosis of moderately severe depression was made and treatment with antidepressants commenced. Over the following 3 weeks the dose of medication was progressively increased, but his mood did not improve, and his complaints of memory and concentration difficulties increased. He was admitted for further assessment and treatment. Neurological examination revealed bilateral hyperreflexia in the lower limbs, sensory loss in a stocking distribution to above the ankles bilaterally, and ataxic gait, Romberg +ve. Extensive investigations revealed no organic cause for his depression. Antidepressant medication was changed from prothiaden to fluoxetine. Over the following 3 weeks his mood improved, and his concentration and memory difficulties resolved. He returned to work 4 weeks after commencing fluoxetine. DE Activities of Daily Living/PSYCHOLOGY Adult AIDS Dementia Complex/DRUG THERAPY/*PSYCHOLOGY Case Report Depressive Disorder/DRUG THERAPY/*PSYCHOLOGY Dothiepin/THERAPEUTIC USE Factitious Disorders/DRUG THERAPY/*PSYCHOLOGY Fluoxetine/THERAPEUTIC USE Homosexuality/PSYCHOLOGY Human Male Neuropsychological Tests MEETING ABSTRACT SOURCE: National Library of Medicine. NOTICE: This material may be protected by Copyright Law (Title 17, U.S.Code).