Document 0693
 DOCN  M94A0693
 TI    A case of HIV-2 infection in Victoria.
 DT    9412
 AU    Breschkin A; Russell D; Crofts N; Locarnini S; Victorian Infectious
       Diseases Reference Laboratory, Fairfield; Hospital.
 SO    Annu Conf Australas Soc HIV Med. 1993 Oct 28-30;5:35 (abstract no. SC2).
       Unique Identifier : AIDSLINE ASHM5/94348962
 AB    In June 1993 a serum sample from a high-risk patient was referred to the
       Victorian HIV Reference Laboratory at Fairfield Hospital for routine
       anti-HIV testing. The serum was repeatedly reactive (S/C0 = 3.7) by the
       Abbott HIV-1/HIV-2 EIA. Confirmatory testing by HIV-1 Western blot
       showed an indeterminate profile with moderate-weak reactivity to P24,
       P34 and P55. The serum was strongly reactive to HIV-2 in the Genetic
       Systems GENIE synthetic envelope peptide assay and was non-reactive to
       HIV-1. The specimen was confirmed positive by HIV-2 Western blot at the
       National Reference Laboratory, showing reactivity to all HIV-2 bands.
       The serum was non-reactive by the Wellcome HIV-1 EIA and the AGEN HIV-1
       SimpliRED assay. Retrospective testing of a July 1991 serum from the
       patient was non-reactive in the HIV-1/HIV-2 ELA. Although HIV-2
       infection is extremely rare in Australia, this case illustrates that the
       potential for its spread obviously exists. It is reassuring that
       Australian diagnostic and blood bank laboratories are now using
       screening assays capable of detecting HIV-1 and HIV-2 infection.
 DE    *AIDS Serodiagnosis  Blotting, Western  Human  HIV
       Infections/*DIAGNOSIS/PREVENTION & CONTROL/TRANSMISSION  *HIV-2
       Immunoenzyme Techniques  MEETING ABSTRACT

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