Document 0694
 DOCN  M94A0694
 TI    Sinusitus in the person with HIV infection.
 DT    9412
 AU    van der Horst C; University of North Carolina.
 SO    Annu Conf Australas Soc HIV Med. 1993 Oct 28-30;5:34 (abstract no. FC5).
       Unique Identifier : AIDSLINE ASHM5/94348961
 AB    Although sinusitus is not a fatal complication of HIV infection it is
       nonetheless a vexing problem for my patients. The incidence and severity
       worsens as CD4 count declines and is often associated with intranasal
       drug use. Higher IgE levels are associated with worse sinusitis and
       atopy. Treatment must include intranasal steroids and perhaps
       decongestants. In the patient with elevated CD4 counts who presents with
       first an initial episode of sinusitis and is not on systemic antibiotics
       such as tmp/smx, rifabutin or clarithromycin empiric therapy with a
       cheap B-lactam is possible. Infections that do not respond or that occur
       in the face of systemic oral therapy warrant a radiologic examination,
       consideration of a sinus tap, and treatment with intravenous
       antibiotics. Chronic infection should suggest infection with fungi,
       anaerobes, staph aureus, and other resistant organisms.
 DE    AIDS-Related Opportunistic Infections/DRUG THERAPY/*ETIOLOGY  Chronic
       Disease  Clarithromycin/THERAPEUTIC USE  Diagnosis, Differential  Human
       Rifabutin/THERAPEUTIC USE  Sinusitis/DRUG THERAPY/*ETIOLOGY
       Trimethoprim-Sulfamethoxazole Combination/THERAPEUTIC USE  MEETING
       ABSTRACT

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